Click Here For Nasal Spray Naloxone Instructions

To Give Injectable Naloxone

You can also view these instructions as a video at the bottom of this page:

1) Call 911

  • Call 911 and put your phone on speaker. NOTE: Both the person(s) seeking help and the overdose victim are protected from drug prosecution if they cooperate with law enforcement.

2) Rescue breathing

Oxygen saves lives. Breathe for them.

  • Make sure nothing is inside the person’s mouth.
  • -One hand on chin, tilt head back, pinch nose closed
  • -Make seal over mouth, breathe into mouth
  • -1 breath every 5 seconds
  • Chest should rise, not stomach

3) Prepare Naloxone

  • Remove cap from naloxone and uncover needle.
  • Insert needle through rubber plug, with bottle upside down.
  • Pull back on plunger and take up 1 cc into the syringe
  • Don’t worry about air bubbles (they aren’t dangerous in muscle injections)

4) Muscular Injection

  • Inject 1 cc of naloxone into a big muscle (shoulder or buttocks)

5) Evaluate & Support

  • Continue rescue breathing.
  • Give a 2nd shot of naloxone in 3 minutes if no or minimal breathing or responsiveness.
  • Give a 3rd shot of naloxone in 3 minutes if no or minimal breathing or responsiveness,
  • Naloxone wears off in 30-90 mins.
  • Comfort them; withdrawal can be unpleasant.
  • Get them medical care and help them not sure more opiate right away.
  • Encourage survivors to seek treatment if they feel they have a problem.